KMT6 Rabbit Monoclonal antibody

Description

EnkiLife offers the KMT6 Rabbit Monoclonal antibody. This antibody reacts with Human,Mouse,Rat species and is suitable for WB,ICC/IF application. Alternative Names of Immunogen: WVS; ENX1; KMT6; WVS2; ENX-1; EZH2b; KMT6A; EZH2. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:1000,ICC/IF 1:50-1:200 Background: Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' and 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate 'Lys-27' of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively. Compared to EZH2-containing complexes, it is more abundant in embryonic stem cells and plays a major role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation. Research Area: Epigenetics and Nuclear Signaling