KO-Validated Apolipoprotein E Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KO-Validated Apolipoprotein E Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human and is suitable for WB,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:APOE; Apolipoprotein E; AD2; Alzheimer Disease 2 (APOE*E4-Associated, Late Onset); Apolipoprotein E3; LDLCQ5; APO-E; ApoE4; Apo-E; LPG Background: The protein encoded by this gene is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. This gene maps to chromosome 19 in a cluster with the related apolipoprotein C1 and C2 genes. Mutations in this gene result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. [provided by RefSeq, Jun 2016] Research Area: Neuroscience,Cardiovascular,Neuroscience,Stem Cells,Signal Transduction,Developmental Biology,Cancer,Metabolism