KO-Validated ATP1A1 Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KO-Validated ATP1A1 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB,IHC-P application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:2,000-1:10,000; IHC-P 1:100-1:200 Alternative Names of Immunogen:ATP1A1; ATPase Na+/K+ Transporting Subunit Alpha 1; Sodium/Potassium-Transporting ATPase Subunit Alpha-1; Sodium Pump Subunit Alpha-1; Sodium-Potassium ATPase Catalytic Subunit Alpha-1; ATPase, Na+/K+ Transporting, Alpha 1 Polypeptide; Na(+)/K(+) ATPase Alpha-1 Subunit; Na,K-ATPase Catalytic Subunit Alpha-A Protein; Sodium-Potassium-ATPase, Alpha 1 Polypeptide; Na, K-ATPase, Alpha-A Catalytic Polypeptide; Na,K-ATPase Alpha-1 Subunit; Na+/K+ ATPase 1; EC 7.2.2.13; EC 3.6.3.9; HOMGSMR2; EC 3.6.3; CMT2DD Background: The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 1 subunit. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009] Research Area: Neuroscience,Signal Transduction,Metabolism