KO-Validated Integrin Subunit Alpha 4 Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KO-Validated Integrin Subunit Alpha 4 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human and is suitable for WB,FCM application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000 Alternative Names of Immunogen:ITGA4; Integrin Subunit Alpha 4; CD49D; Alpha 4 Subunit Of VLA-4 Receptor; CD49 Antigen-Like Family Member D; VLA-4 Subunit Alpha; Integrin Alpha-IV; Integrin Alpha-4; Integrin, Alpha 4 (Antigen CD49D, Alpha 4 Subunit Of VLA-4 Receptor); Very Late Activation Protein 4 Receptor, Alpha 4 Subunit; Antigen CD49D, Alpha-4 Subunit Of VLA-4 Receptor; 269C Wild Type; Antigen CD49D; CD49d Antigen; CD49d; IA4 Background: The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 4 subunit. This subunit associates with a beta 1 or beta 7 subunit to form an integrin that may play a role in cell motility and migration. This integrin is a therapeutic target for the treatment of multiple sclerosis, Crohn's disease and inflammatory bowel disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015] Research Area: Immunology,Signal Transduction,Stem Cells,Cardiovascular