KO-Validated Phospho-Histone H2A.X (S139) Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KO-Validated Phospho-Histone H2A.X (S139) Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB,FCM,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:2,000-1:10,000; FC 1:200-1:2,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:H2AX; H2A.X Variant Histone; H2AFX; H2A Histone Family Member X; Histone H2A.X; Histone H2AX; H2A Histone Family, Member X; H2AX Histone; H2A.X; H2A/X; H2a/X; γ-H2AX Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. [provided by RefSeq, Oct 2015] Research Area: Epigenetics and Nuclear Signaling