KO-Validated Phospho-IGF1 Receptor (Y1166) Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KO-Validated Phospho-IGF1 Receptor (Y1166) Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB,FCM application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000 Alternative Names of Immunogen:IGF1R; Insulin Like Growth Factor 1 Receptor; Insulin-Like Growth Factor 1 Receptor; JTK13; CD221; IGFIR; IGFR; IGF-I Receptor; EC 2.7.10.1; MGC18216; Insulin-Like Growth Factor I Receptor; CD221 Antigen; EC 2.7.10 Background: This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014] Research Area: Developmental Biology