KO-Validated Phospho-POLR2A (S5) Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KO-Validated Phospho-POLR2A (S5) Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000 Alternative Names of Immunogen:RNA Polymerase II Subunit A; RNA Polymerase II Subunit B1; POLRA; POLR2; RPB1; DNA-Directed RNA Polymerase II Largest Subunit, RNA Polymerase II 220 Kd Subunit; Polymerase (RNA) II (DNA Directed) Polypeptide A, 220kDa; DNA-Directed RNA Polymerase III Largest Subunit; DNA-Directed RNA Polymerase II Subunit RPB1; RNA-Directed RNA Polymerase II Subunit RPB1; DNA-Directed RNA Polymerase II Subunit A; EC 2.7.7.6; Polymerase (RNA) II Subunit A; EC 2.7.7.48; HRPB220; NEDHIB; RpIILS; HsRPB1; RPBh1; RPOL2; RPO2 Background: This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA. [provided by RefSeq, Jul 2008] Research Area: Epigenetics and Nuclear Signaling