KO-Validated Phospho-SIRT1 (S47) Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KO-Validated Phospho-SIRT1 (S47) Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human and is suitable for WB application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000 Alternative Names of Immunogen:SIRT1; Sirtuin; SIR2L1; NAD-Dependent Protein Deacetylase Sirtuin-1; NAD-Dependent Protein Deacylase Sirtuin-1; Regulatory Protein SIR2 Homolog 1; SIR2-Like Protein 1; Sirtuin (Silent Mating Type Information Regulation 2, S. Cerevisiae, Homolog); Sirtuin (Silent Mating Type Information Regulation 2 Homolog) 1 (S. Cerevisiae); Sirtuin Type 1; EC 2.3.1.286; EC 2.3.1.- ; SIR2alpha; HSIRT1; HSIR2; SIR2 Background: This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008] Research Area: Cell Biology,Epigenetics and Nuclear Signaling,Metabolism,Microbiology