KO-Validated Progesterone Receptor Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KO-Validated Progesterone Receptor Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human and is suitable for WB,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:PGR; Progesterone Receptor; NR3C3; PR; Nuclear Receptor Subfamily 3 Group C Member 3 Background: This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce several transcript variants, both protein coding and non-protein coding. Two of the isoforms (A and B) are identical except for an additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap. [provided by RefSeq, Sep 2015] Research Area: Epigenetics and Nuclear Signaling,Signal Transduction,Neuroscience,Cancer