KO-Validated SMAC Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KO-Validated SMAC Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat and is suitable for WB,FCM,ICC application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000; FC 1:200-1:2,000; ICC 1:100-1:1,000 Alternative Names of Immunogen:Diablo; IAP-Binding Mitochondrial Protein; DFNA64; Second Mitochondria-Derived Activator Of Caspase; Diablo Homolog; Mitochondrial; SMAC; Smac; Direct IAP-Binding Protein With Low PI Background: This gene encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and allows activation of caspases by binding to inhibitor of apoptosis proteins. Overexpression of the encoded protein sensitizes tumor cells to apoptosis. A mutation in this gene is associated with young-adult onset of nonsyndromic deafness-64. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013] Research Area: Cell Biology,Cancer,Metabolism