KO-Validated STAT2 Recombinant Rabbit Monoclonal Antibody

Description

EnkiLife offers the KO-Validated STAT2 Recombinant Rabbit Monoclonal Antibody. This antibody reacts with Human,Rat and is suitable for WB application. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:1,000-1:5,000 Alternative Names of Immunogen:STAT2; Signal Transducer And Activator Of Transcription 2; STAT113; Signal Transducer And Activator Of Transcription 2, 113kDa; P113; Signal Transducer And Activator Of Transcription 2, 113kD; Interferon Alpha Induced Transcriptional Activator; PTORCH3; ISGF-3; IMD44 Background: The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. The protein mediates innate antiviral activity. Mutations in this gene result in Immunodeficiency 44. [provided by RefSeq, Aug 2020] Research Area: Epigenetics and Nuclear Signaling,Microbiology,Signal Transduction