

HY-161539 · 50 mg
MedChemExpress · Cat: HY-161539
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Manufacturer product page
medchemexpress.com/kor-agonist-1.html
Description
KOR agonist 1 Compound 7a is a selective agonist for opioid receptor, with EC50s of 3.4, 701.2 and 1649 nM, for KOR, MOR and DOR, respectively. KOR agonist 1 binds KOR, MOR and DOR, with Kis of 3.9, 1053 and 4196 nM, respectively. KOR agonist 1 exhibits antinociceptive effect in ICR mouse model ED50 in hot plate test is 0.3 mg/kg, in abdominal constriction test is 0.2 mg/kg .







