GENERAL CATALOGUE
KR-39038
HY-143248 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-143248
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Manufacturer product page
medchemexpress.com/kr-39038.htmlCatalog No: HY-143248
CAS No: 2770300-35-9
Category: Cell Cycle DNA Damage
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
KR-39038 is an orally active and potent GRK5 G protein-coupled receptor kinase 5 inhibitor, with an IC50 of 0.02 ?M. KR-39038 significantly inhibits angiotensin II-induced cellular hypertrophy through suppression of HDAC5 pathway in neonatal cardiomyocytes. KR-39038 shows profound anti-hypertrophic effects and improved cardiac function. KR-39038 can be used for heart failure research.
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