

HY-151523 · 1 mg
MedChemExpress · Cat: HY-151523
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Manufacturer product page
medchemexpress.com/kras-g12r-inhibitor-1.html
Description
KRas G12R inhibitor 1 is a covalent inhibitor targeting the common oncogenic mutant KRas G12R with selectivity for the mutant arginine. KRas G12R inhibitor 1 possesses an ?,?-diketoamide and exploits strong nucleophilicity of the mutant cysteine and irreversibly binds in the Switch II region of KRas. KRas G12R inhibitor 1 can be researched for K-Ras G12R -driven cancer such as pancreatic ductal adenocarcinoma PDAC .







