GENERAL CATALOGUE
KRAS G13D-IN-1
HY-161066 · 50 mg
MedChemExpress · Cat: HY-161066
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medchemexpress.com/kras-g13d-in-1.html
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Catalog No: HY-161066
Category: GPCR G Protein
Pack Size: 50 mg
Brand: MedChemExpress
Description
KRAS G13D-IN-1 compound 41 is a selective and covalently reversible inhibitor of KRASG13D IC50: 0.41 nM . The selectivity for KRASG13D is 29-fold against KRAS wild type. KRAS G13D-IN-1 is an inhibitor of the GDP state and targets the SWII binding pocket of KRASG13D. KRAS G13D-IN-1 inhibits KRAS binding to GDP and turns on/off downstream signaling cascades.
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