

HY-174379 · 50 mg
MedChemExpress · Cat: HY-174379
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Manufacturer product page
medchemexpress.com/kras-in-44.html
Description
KRAS IN-44 Compound S2C2M2 is a PDE6D degrader. KRAS IN-44 inhibits PDE6D-dependent KRAS trafficking and KRAS downstream signaling pathways. KRAS IN-44 down-regulates EGF-induced the phosphorylation of PI3K, AKT, and mTOR. KRAS IN-44 increases Apoptosis. KRAS IN-44 has antitumor activity against hepatoblastoma.







