GENERAL CATALOGUE
KRAS inhibitor-12
HY-146533 · 50 mg
MedChemExpress · Cat: HY-146533
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medchemexpress.com/kras-inhibitor-12.htmlCatalog No: HY-146533
CAS No: 2230874-00-5
Category: GPCR G Protein
Pack Size: 50 mg
Brand: MedChemExpress
Description
KRAS inhibitor-12 compound 6-1 is a potent KRAS G12C inhibitor with an IC50 of 0.537 AAasAasAAmuM. KRAS inhibitor-12 shows p-ERK inhibition activities with IC50s of 1.3, 3.7 AAasAasAAmuM in MIA PaCA-2, A549 cells, respectively. KRAS inhibitor-12 has the potential for the research of pancreatic, colorectal, and lung cancers.
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