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KRAS inhibitor-18
GENERAL CATALOGUE

KRAS inhibitor-18

HY-146476 · 50 mg

MedChemExpress · Cat: HY-146476

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Catalog No: HY-146476
CAS No: 2230873-66-0
Category: GPCR G Protein
Pack Size: 50 mg
Brand: MedChemExpress

Description

KRAS inhibitor-18 compound 3-10 is a potent KRAS G12C inhibitor with an IC50 of 4.74 AAasAasAAmuM. KRAS inhibitor-18 shows p-ERK inhibition activities with IC50s of 66.4, 11.1 AAasAasAAmuM in MIA PaCA-2, A549 cells, respectively. KRAS inhibitor-18 has the potential for the research of pancreatic, colorectal, and lung cancers.

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