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KRAS inhibitor-27
GENERAL CATALOGUE

KRAS inhibitor-27

HY-164350 · 1 mg

MedChemExpress · Cat: HY-164350

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Catalog No: HY-164350
CAS No: 3033690-83-1
Category: GPCR G Protein
Pack Size: 1 mg
Brand: MedChemExpress

Description

KRAS inhibitor-27 Compound 15h is the inhibitor for KRAS. KRAS inhibitor-27 inhibits KRAS G12D/G12V mutated cells AsPC-1, SW620 and KRAS wildtype cell HT-29 with IC50 of 378, 0.6 and 3230 nM, respectively. KRAS inhibitor-27 inhibits ERK phosphorylation IC50 in cell AsPC-1 and SW620 is 0.6 nM and 1 nM , reduces the expression of DUSP4, thereby inhibiting MAPK signaling pathway.

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