

HY-115672 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-115672
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medchemexpress.com/ks15.htmlDescription
KS15 is an inhibitor of the interactions between cryptochromes CRYs: CRY1 and CRY2 and the CLOCK:BMAL1 heterodimer. KS15 impairs the feedback actions of CRYs on E-box-dependent transcription EC50=4.9 ?M by CLOCK:BMAL1 heterodimer, an indispensable transcriptional regulator of the mammalian circadian clock. Anti-proliferative activity.







