GENERAL CATALOGUE
KSC-34
HY-117570 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-117570
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Manufacturer product page
medchemexpress.com/ksc-34.htmlCatalog No: HY-117570
CAS No: 2226201-97-2
Category: Cell Cycle DNA Damage
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
KSC-34, a covalent modifier of protein disulfide isomerase A1 PDIA1 , is also a selective and potent a-site inhibitor of PDIA1 with an IC50 of 3.5 ?M. KSC-34 displays a 30-fold selectivity for a domain over a? domain and displays high selectivity for PDIA1 in complex proteomes with minimal engagement of other members of the PDI family. KSC-34 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition CuAAc with molecules containing Azide groups.
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