Ksr2 Rabbit Polyclonal Antibody

Description

EnkiLife offers the Ksr2 Rabbit Polyclonal Antibody. This antibody reacts with Human,Mouse species and is suitable for WB,IHC,ICC/IF,ELISA application. Alternative Names of Immunogen: KSR2; Kinase suppressor of Ras 2; hKSR2. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:2000,IHC 1:100-1:300,ICC/IF 1:200-1:1000,ELISA 1:20000-1:40000 Background: domain:The protein kinase domain is predicted to be catalytically inactive. function:Location-regulated scaffold connecting MEK to RAF. Blocks MAP3K8 kinase activity and MAP3K8-mediated signaling. Acts as a negative regulator of MAP3K3-mediated activation of ERK, JNK and NF-kappa-B pathways, inhibiting MAP3K3-mediated interleukin-8 production. PTM:Phosphorylated on Ser-474 by MARK3. similarity:Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. similarity:Contains 1 phorbol-ester/DAG-type zinc finger. similarity:Contains 1 protein kinase domain. subunit:Interacts with MAP2K1, MAP3K8, MAPK, RAS and RAF. tissue specificity:Mainly expressed in brain and kidney.