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Kv2.1-IN-1
GENERAL CATALOGUE

Kv2.1-IN-1

HY-161104 · 10 mM * 1 mL in DMSO

MedChemExpress · Cat: HY-161104

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Manufacturer product page

medchemexpress.com/kv2-1-in-1.html
Catalog No: HY-161104
CAS No: 2252448-93-2
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress

Description

Kv2.1-IN-1 is an orally active and blood-brain barrier penetrant Kv2.1 inhibitor with an IC50 of 0.07 ?M. Kv2.1-IN-1 exhibits a selectivity >130 fold over other K+, Na+, and Ca2+ ion channels. Kv2.1-IN-1 decreases the apoptosis of HEK293 cells induced by H2O2. Kv2.1-IN-1 produces significant neuroprotection efficacy in middle cerebral artery occlusion MCAO rat. Kv2.1-IN-1 can be used for the study of ischemic stroke.

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