GENERAL CATALOGUE
KWZY-11
HY-176713 · 50 mg
MedChemExpress · Cat: HY-176713
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Manufacturer product page
medchemexpress.com/kwzy-11.htmlCatalog No: HY-176713
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
KWZY-11 Compound 11 is a potent PARP/CDK6 dual inhibitor with IC50 values of 156.8, 197.3, and 13.3 nM for PARP1, PARP2, and CDK6, respectively. KWZY-11 inhibits tumor cell proliferation by regulating the Wnt/?-catenin signaling pathway. KWZY-11 induces excessive DNA damage and apoptosis in MDA-MB-231 breast cancer cells.
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