GENERAL CATALOGUE
KY-05009
HY-124745 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-124745
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medchemexpress.com/ky-05009.html
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Catalog No: HY-124745
CAS No: 1228280-29-2
Category: Apoptosis
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
KY-05009 is an ATP-competitive Traf2- and Nck-interacting kinase TNIK inhibitor with a Ki of 100 nM. KY-05009 pharmacologically inhibits TGF-?1-induced epithelial-to-mesenchymal transition EMT in human lung adenocarcinoma cells. KY-05009 inhibits the protein expression of TNIK and transcriptional activity of Wnt target genes and induces apoptosis in cancer cells. KY-05009 exerts anti-cancer activity.
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