L-006235 (Standard)

Description

L-006235 Standard is the analytical standard of L-006235. This product is intended for research and analytical applications. L-006235 L-235 is a potent, selective, reversible and orally active inhibitor of cathepsin K, with an IC50 of 5 nM in bone resorption assay. L-006235 shows selectivity for cathepsin K Ki=0.2 nM over cathepsin B, cathepsin L, and cathepsin S Ki=1, 6, and 47 ?M, respectively . L-006235 can reduce collagen degradation and prevent bone loss.