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L-732138
GENERAL CATALOGUE

L-732138

HY-101249 · Free Sample (0.1 - 0.2 mg)

MedChemExpress · Cat: HY-101249

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medchemexpress.com/l-732138.html
Catalog No: HY-101249
CAS No: 148451-96-1
Category: GPCR G Protein
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress

Description

L-732138 is a selective, potent and competitive neurokinin-1 NK-1 receptor antagonist with an IC50 of 2.3 nM. L-732138 has 200-fold more potent in cloned human NK-1 receptors than cloned rat NK-1 receptors, and has > 1000-fold more potent than human NK-2 and NK-3 receptors. L-732138 can reduce hyperalgesia and has antitumor action.

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