GENERAL CATALOGUE
L 741742
HY-101349 · 50 mg
MedChemExpress · Cat: HY-101349
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medchemexpress.com/l-741742.htmlCatalog No: HY-101349
CAS No: 156337-32-5
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
L 741742 is a dopamine receptor D4 DRD4 antagonist that selectively inhibits glioblastomas GBM growth in vitro and in vivo, synergyed with Temozolomide TMZ HY-17364 . L 741742 disrupts in effectors PDGFR?/ERK1/2 and mTOR signaling. Additionally, L 741742 disrupts endolysosmal function compromising the autophagy-lysosomal degradation pathway, followed by G0/G1 cell cycle arrest and Apoptosis. L 741742 is promising for research of GBM and neurogenesis.
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