GENERAL CATALOGUE
L-745870
HY-14325 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-14325
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Manufacturer product page
medchemexpress.com/l-745870.htmlCatalog No: HY-14325
CAS No: 158985-00-3
Category: GPCR G Protein
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
L-745870 is a potent, selective, brain-penetrant and orally active dopamine D4 receptor antagonist with a Ki of 0.43 nM. L-745870 shows weaker affinity for D2 Ki of 960 nM and D3 Ki of 2300 nM receptors, and exhibits moderate affinity for 5-HT2 receptors, sigma sites and ?-adrenoceptors.
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