GENERAL CATALOGUE
L-764406
HY-121579 · 50 mg
MedChemExpress · Cat: HY-121579
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medchemexpress.com/l-764406.html
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Catalog No: HY-121579
CAS No: 227002-04-2
Category: Cell Cycle DNA Damage
Pack Size: 50 mg
Brand: MedChemExpress
Description
L-764406 is a non-thiazolidinedione TZD -type PPARg nuclear receptor ligand with high affinity. L-764406 has significant binding ability to PPARg IC50=70 nM . L-764406 exhibited partial agonist activity and induced expression of the adipocyte-specific gene aP2 in chimeric receptors expressing the PPARg LBD and the corresponding reporter gene, as well as in 3T3-L1 cells. In contrast, L-764406 showed no activity in cells transfected with chimeric receptors containing PPARa or PPARd LBDs.
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