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L-Buthionine-(S,R)-sulfoximine
GENERAL CATALOGUE

L-Buthionine-(S,R)-sulfoximine

HY-106376A · 10 mM * 1 mL in Water

MedChemExpress · Cat: HY-106376A

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Catalog No: HY-106376A
CAS No: 83730-53-4
Category: Apoptosis
Pack Size: 10 mM * 1 mL in Water
Brand: MedChemExpress

Description

L-Buthionine- S,R -sulfoximine is a cell-permeable, potent, fast acting and irreversible inhibitor of g-glutamylcysteine synthetase and depletes cellular glutathione levels. The IC50 value of L-Buthionine- S,R -sulfoximine on melanoma, breast and ovarian tumor specimens are 1.9 ?M, 8.6 ?M, and 29 ?M, respectively.

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