GENERAL CATALOGUE
L1BC8
HY-164995 · 100 g
MedChemExpress · Cat: HY-164995
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Catalog No: HY-164995
CAS No: 2417370-68-2
Category: Antibody-drug Conjugate ADC Related
Pack Size: 100 g
Brand: MedChemExpress
Description
L1BC8 compound 13a is a BRD4 PROTAC degrader with anticancer effects. L1BC8 is also a drug-linker conjugate for ADC that can be used for the synthesis of ADCs. The resulting BRD4-degrader antibody conjugates exhibit potent and antigen-dependent BRD4 degradation and antiproliferation activities in cell-based experiments. Pink: BRD4 ligand HY-129939 ; Blue: VHL ligand HY-125845 ; Black: linker HY-171663 .
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