GENERAL CATALOGUE
LAB687
HY-177291 · 50 mg
MedChemExpress · Cat: HY-177291
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Catalog No: HY-177291
CAS No: 256397-11-2
Category: Metabolic Enzyme Protease
Pack Size: 50 mg
Brand: MedChemExpress
Description
LAB687 Compound 2a is a Microsomal triglyceride transfer protein MTP inhibitor with an IC50 of 0.9 ?nM for the secretion of apoB from HepG2 cells. LAB687 is also a Smoothened Smo antagonist with IC50s of 2.48 and 3.42 ?M for mouse and human Smo receptor, respectively. LAB687 can lower the level of triglycerides and LDL cholesterol and inhibits the Hedgehog signaling pathway.
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