GENERAL CATALOGUE
Laduviglusib monohydrochloride
HY-10182A · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-10182A
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Manufacturer product page
medchemexpress.com/laduviglusib-monohydrochloride.htmlCatalog No: HY-10182A
CAS No: 1797989-42-4
Category: Autophagy
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Laduviglusib CHIR-99021 monohydrochloride is a potent and selective GSK-3?/? inhibitor with IC50s of 10 nM and 6.7 nM. Laduviglusib monohydrochloride shows >500-fold selectivity for GSK-3 over CDC2, ERK2 and other protein kinases. Laduviglusib monohydrochloride is also a potent Wnt/?-catenin signaling pathway activator. Laduviglusib monohydrochloride enhances mouse and human embryonic stem cells self-renewal. Laduviglusib monohydrochloride induces autophagy.
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