GENERAL CATALOGUE
Laduviglusib trihydrochloride
HY-10182B · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-10182B
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medchemexpress.com/laduviglusib-trihydrochloride.htmlCatalog No: HY-10182B
CAS No: 1782235-14-6
Category: Autophagy
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
Laduviglusib CHIR-99021 trihydrochloride is a potent and selective GSK-3?/? inhibitor with IC50s of 10 nM and 6.7 nM. Laduviglusib trihydrochloride shows >500-fold selectivity for GSK-3 over CDC2, ERK2 and other protein kinases. Laduviglusib trihydrochloride is also a potent Wnt/?-catenin signaling pathway activator. Laduviglusib trihydrochloride enhances mouse and human embryonic stem cells self-renewal. Laduviglusib trihydrochloride induces autophagy.
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