GENERAL CATALOGUE
Lasmotinib
HY-153857 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-153857
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medchemexpress.com/phi-101.html
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Catalog No: HY-153857
CAS No: 2127107-15-5
Category: Cell Cycle DNA Damage
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Lasmotinib PHI-101 is a FLT3 and CHK2 inhibitor. Lasmotinib potently inhibits FLT3 single activating mutations ITD or TKD mutants and has inhibitory activity against FLT3 double ITD/D835Y or ITD/F691L and triple ITD/D835Y/F691L resistance mutations. Lasmotinib synergizes with Venetoclax HY-15531 or Azacytidine to inhibit leukemia. Lasmotinib exhibits anticancer activity against ovarian and breast cancer.
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