GENERAL CATALOGUE
LD4172
HY-153598 · 1 mg
MedChemExpress · Cat: HY-153598
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Catalog No: HY-153598
CAS No: 2782022-40-4
Category: Apoptosis
Pack Size: 1 mg
Brand: MedChemExpress
Description
LD4172 is a PROTAC degrader for RIP kinase RIPK1 with DC50 in nanomolare levels. LD4172 induces apoptosis in cell B16F10 with combination of TNF-?. LD4172 exhibits antitumor efficacy in mouse models. Pink: ligand for target protein HY-170613 ; Black: linker HY-W012241 ; Blue: ligand for E3 ligase VHL HY-112078
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