Leflunomide Related Compound B

Description

rac A77 1726 is the active metabolite of Leflunomide, a potent diseasemodifying antirheumatic drug used in the treatment of rheumatoid arthritis. LEFM interferes with dendritic cell function. The second Phase III study evaluating the efficacy of Genzymes teriflunomide therapy against relapsing forms of multiple sclerosis found the oncedaily oral drug to be no less effective than injectable interferon beta 1a Rebif .