

HY-112828 · 50 mg
MedChemExpress · Cat: HY-112828
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medchemexpress.com/lei105.htmlDescription
LEI105 is a potent, highly selective and reversible dual diacylglycerol lipase DAGL -?/DAGL-? inhibitor. LEI105 reduces 2-arachidonoylglycerol levels in Neuro2A cells. LEI105 also reduces cannabinoid CB1-receptor-mediated short-term synaptic plasticity in a mouse hippocampal slice model. LEI105 is promising for research of diseases, such as obesity, related metabolic disorders and neuroinflammation.







