GENERAL CATALOGUE
LEM-14
HY-114340 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-114340
₹250 – ₹380 approx.This price excludes freight and taxes. Please RFQ to get the final price.
Reach 3+ verified distributors
Manufacturer product page
medchemexpress.com/lem-14.html
Sponsored
Catalog No: HY-114340
CAS No: 1814881-70-3
Category: Epigenetics
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
LEM-14 is a potent and selective NSD2 inhibitor with an IC50 of 132 AAasAasAAmuM. LEM-14 has very weak activitv against NSD1 and has no activity against NSD3. LEM-14 inhibits fibrotic gene expression in ND but not DIO BMDMs. LEM-14 combined with ionizing radiation IR enhances the apoptosis rate and reduces the colony-formation ability of CRC cells. LEM-14 exhibits enhanced anti-tumor efficacy in Balb/c nude mice bearing LoVo cell xenografts when combined with ionizing radiation. LEM-14 has the potential for the research of multiple myeloma and colorectal cancer.
More from MedChemExpress
H
hsa-miR-4268 antagomir
HY-RI00947A
Epigenetics
H
hsa-miR-4731-5p antagomir
HY-RI01332A
Epigenetics
F
FRMD3 Human Pre-designed siRNA Set A
HY-RS05100
Epigenetics
M
MAPK12 Human Pre-designed siRNA Set A
HY-RS08101
Epigenetics
N
NEURL1 Human Pre-designed siRNA Set A
HY-RS09219
Epigenetics
L
LRFN2 Human Pre-designed siRNA Set A
HY-RS07782
Epigenetics
Luteolin 7-sulfate
HY-N6901
Epigenetics
VRTN Human Pre-designed siRNA Set A
HY-RS15705
Epigenetics