GENERAL CATALOGUE
Lenalidomide-13C5,15N
HY-A0003S2 · 1 mg
MedChemExpress · Cat: HY-A0003S2
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Manufacturer product page
medchemexpress.com/lenalidomide-13c5-15n.htmlCatalog No: HY-A0003S2
Category: Apoptosis
Pack Size: 1 mg
Brand: MedChemExpress
Description
Lenalidomide-13C5,15N is 15N and 13C labeled Lenalidomide HY-A0003 . Lenalidomide CC-5013 , a derivative of Thalidomide, acts as molecular glue. Lenalidomide is an orally active immunomodulator. Lenalidomide CC-5013 is a ligand of ubiquitin E3 ligase cereblon CRBN , and it causes selective ubiquitination and degradation of two lymphoid transcription factors, IKZF1 and IKZF3, by the CRBN-CRL4 ubiquitin ligase. Lenalidomide CC-5013 specifically inhibits growth of mature B-cell lymphomas, including multiple myeloma, and induces IL-2 release from T cells.
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