GENERAL CATALOGUE
Lenalidomide-d5
HY-A0003S · 1 mg
MedChemExpress · Cat: HY-A0003S
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Catalog No: HY-A0003S
CAS No: 1227162-34-6
Category: Apoptosis
Pack Size: 1 mg
Brand: MedChemExpress
Description
Lenalidomide-d5 is deuterium labeled Lenalidomide. Lenalidomide CC-5013 , a derivative of Thalidomide, acts as molecular glue. Lenalidomide is an orally active immunomodulator. Lenalidomide CC-5013 is a ligand of ubiquitin E3 ligase cereblon CRBN , and it causes selective ubiquitination and degradation of two lymphoid transcription factors, IKZF1 and IKZF3, by the CRBN-CRL4 ubiquitin ligase. Lenalidomide CC-5013 specifically inhibits growth of mature B-cell lymphomas, including multiple myeloma, and induces IL-2 release from T cells.
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