

HY-A0003B · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-A0003B
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medchemexpress.com/Lenalidomide-hemihydrate.html
Description
Lenalidomide hemihydrate CC-5013 hemihydrate , a derivative of Thalidomide, acts as molecular glue. Lenalidomide hemihydrate is an orally active immunomodulator. Lenalidomide hemihydrate CC-5013 hemihydrate is a ligand of ubiquitin E3 ligase cereblon CRBN , and it causes selective ubiquitination and degradation of two lymphoid transcription factors, IKZF1 and IKZF3, by the CRBN-CRL4 ubiquitin ligase. Lenalidomide hemihydrate CC-5013 hemihydrate specifically inhibits growth of mature B-cell lymphomas, including multiple myeloma, and induces IL-2 release from T cells.







