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Lenalidomide hemihydrate
GENERAL CATALOGUE

Lenalidomide hemihydrate

HY-A0003B · Free Sample (0.1 - 0.2 mg)

MedChemExpress · Cat: HY-A0003B

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Catalog No: HY-A0003B
CAS No: 847871-99-2
Category: Apoptosis
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress

Description

Lenalidomide hemihydrate CC-5013 hemihydrate , a derivative of Thalidomide, acts as molecular glue. Lenalidomide hemihydrate is an orally active immunomodulator. Lenalidomide hemihydrate CC-5013 hemihydrate is a ligand of ubiquitin E3 ligase cereblon CRBN , and it causes selective ubiquitination and degradation of two lymphoid transcription factors, IKZF1 and IKZF3, by the CRBN-CRL4 ubiquitin ligase. Lenalidomide hemihydrate CC-5013 hemihydrate specifically inhibits growth of mature B-cell lymphomas, including multiple myeloma, and induces IL-2 release from T cells.

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