GENERAL CATALOGUE
Lenalidomide
HY-A0003 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-A0003
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medchemexpress.com/Lenalidomide.html
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Catalog No: HY-A0003
CAS No: 191732-72-6
Category: Apoptosis
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
Lenalidomide CC-5013 , a derivative of Thalidomide, acts as molecular glue. Lenalidomide is an orally active immunomodulator. Lenalidomide CC-5013 is a ligand of ubiquitin E3 ligase cereblon CRBN , and it causes selective ubiquitination and degradation of two lymphoid transcription factors, IKZF1 and IKZF3, by the CRBN-CRL4 ubiquitin ligase. Lenalidomide CC-5013 specifically inhibits growth of mature B-cell lymphomas, including multiple myeloma, and induces IL-2 release from T cells.
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