GENERAL CATALOGUE
Lepadin E
HY-155851 · 50 mg
MedChemExpress · Cat: HY-155851
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Catalog No: HY-155851
CAS No: 444914-19-6
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
Lepadin E is a significantly cytotoxic ferroptosis inducer that induces iron death through the classical p53-SLC7A11-GPX4 pathway. Lepadin E promoted p53 expression, decreases SLC7A11 and GPX4 levels, and leads to increased ROS and lipid peroxide production, and upregulated ACSL4 expression, thus causes cell death. Lepadin E has significant antitumor effect.
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