GENERAL CATALOGUE
Lestaurtinib
HY-50867 · 1 mg
MedChemExpress · Cat: HY-50867
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Catalog No: HY-50867
CAS No: 111358-88-4
Category: Apoptosis
Pack Size: 1 mg
Brand: MedChemExpress
Description
Lestaurtinib CEP-701 is an orally active and selective RPTKs receptor protein tyrosine kinase inhibitor, competitively inhibits ATP binding to the TrkA/B/C domain. Lestaurtinib inhibits RPTKs phosphorylation, with IC50s of 2, 25 and 0.9 nM for FLT3, TrkA and JAK2, respectively. Lestaurtinib induces apoptosis and cycle arrest, also can inhibit growth of tumor.
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