GENERAL CATALOGUE
Leu-AMS
HY-108900 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-108900
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medchemexpress.com/Leu-AMS.htmlCatalog No: HY-108900
CAS No: 288591-93-5
Category: Anti-infection
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
Leu-AMS compound 6 , a leucine analogue, is a potent inhibitor of leucyl-tRNA synthetase LRS with an IC50 of 22.34 nM, which inhibits the catalytic activity of LRS but did not affect the leucine-induced mTORC1 activation. Leu-AMS shows cytotoxicity in cancer cells and normal cells, and inhibits the growth of bacteria.
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