GENERAL CATALOGUE
Leukadherin-1 (Standard)
HY-15701R · 5 mg
MedChemExpress · Cat: HY-15701R
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medchemexpress.com/leukadherin-1-standard.htmlCatalog No: HY-15701R
CAS No: 344897-95-6
Category: Cytoskeleton
Pack Size: 5 mg
Brand: MedChemExpress
Description
Leukadherin-1 Standard is the analytical standard of Leukadherin-1. This product is intended for research and analytical applications. Leukadherin-1, a specific agonist of the leukocyte surface integrin CD11b/CD18, increases CD11b/CD18-dependent cell adhesion to fibrinogen with an EC50 of 4 ?M. Leukadherin-1 enhances leukocyte adhesion to ligands such as ICAM-1 and vascular endothelium and thus reduces leukocyte transendothelial migration and influx to the injury sites. Leukadherin-1 suppresses innate inflammatory signaling.
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