GENERAL CATALOGUE
Leukotriene B5
HY-113484 · 25 g
MedChemExpress · Cat: HY-113484
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medchemexpress.com/leukotriene-b5.htmlCatalog No: HY-113484
CAS No: 80445-66-5
Category: GPCR G Protein
Pack Size: 25 g
Brand: MedChemExpress
Description
Leukotriene B5 LTB5 is a leukotriene with diverse biological activities. It is a metabolite of eicosapentaenoic acid formed through the 5-lipoxygenase 5-LO pathway. LTB5 increases contraction of bullfrog lung strips ex vivo in a concentration-dependent manner. In vivo, LTB5 100 nM reduces tumor volume in mice injected with Tm1 murine melanoma cells. LTB5 also elicits chemokinesis and lysosomal enzyme release from polymorphonuclear leukocytes PMNLs 20- to 30-fold less, and induces platelet aggregation 8-fold less, potently than LTB4.
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