GENERAL CATALOGUE
LeuRS-IN-1 hydrochloride
HY-139987A · 1 mg
MedChemExpress · Cat: HY-139987A
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medchemexpress.com/leurs-in-1-hydrochloride.html
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Catalog No: HY-139987A
CAS No: 1364683-67-9
Category: Anti-infection
Pack Size: 1 mg
Brand: MedChemExpress
Description
LeuRS-IN-1 hydrochloride is a potent, orally active M. tuberculosis leucyl-tRNA synthetase M.tb LeuRS inhibitor. LeuRS-IN-1 hydrochloride has IC50 and Kd values of 0.06 ?M, 0.075 ?M for M.tb LeuRS, respectively. LeuRS-IN-1 hydrochloride inhibits human cytoplasmic LeuRS IC50=38.8 ?M , and HepG2 protein synthesis EC50=19.6 ?M .
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